http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0249799-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 |
filingDate | 1989-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d0996f5ed72d18ebd2f31194d9a6842 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07de6eb4eec4e1e2d6a943202cd1c890 |
publicationDate | 1990-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H0249799-A |
titleOfInvention | Production of peptide |
abstract | PURPOSE: To obtain peptides using a protecting group capable of removal under so mild conditions as to be stable against acids, bases and reduction by protecting a imidazole group of histidine with 4-methoxy-2,3,6-trimethylbenzenesulfonyl group and synthesizing a peptide. n CONSTITUTION: In production of a peptide containing histidines, imidazole groups of the histidines are reacted with 4-methoxy-2,3,6-trimethylbenzenesulfonyl chloride to form histidine derivatives represented by the formula (R is H or protective group of-amino group; 4-Methoxy-2,3,6-trimethylbenzenesulfonyl group is bonded to N at 1 or 3 position of A ring.) where each imidazole group is protected with a 4-methoxy-2,3,6-trimethylbenzenesulfonyl group and then peptide condensation is carried out. The protecting groups are subsequently removed using an acid or 1-hydroxybenzotriazole to produce the objective peptide. n COPYRIGHT: (C)1990,JPO&Japio |
priorityDate | 1989-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.