| abstract |
PURPOSE: To obtain economically an optically active substituted benzyl alcohol having insecticdial activity by reacting (R,S)α-cyano-3phenoxybenzyl alcohol with a specific compound in the presence of an acid agent to give an optically active intermediate ether and hydrolyzing the ether. n CONSTITUTION: (R,S) α-Cyano-3-phenoxybenzyl alcohol is reacted with cis-2,2- dimethyl-3S-(dihydroxymethyl)cyclopropane-1R-carboxylic acid lactone in the presence of an acid agent to obtain a mixture of two isomers, which are subsequently separated by physical means. (1R,5S) 6,6-dimethyl4R-[(S)-cyano-(3'- phenoxyphenyl)methoxy]-3-oxabicyclo[3,1,0]hexan-2-one is hydrolyzed in an acid medium to give (S) α-cyano-3-phenoxybenzyl alcohol of the formula. n COPYRIGHT: (C)1990,JPO |