http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0249742-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8b9c1f73d1f541b96b213e7a702a8c0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-56 |
| filingDate | 1988-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f67d4b9147f7c11fff4e5030407e7de8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2487d983023a8a5da2cfb71c0452566 |
| publicationDate | 1990-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0249742-A |
| titleOfInvention | Optically active fluorine-containing alpha-hydroxycyclopropane compound |
| abstract | NEW MATERIAL:An optically active fluorine-containing α-hydroxycyclopropane compound expressed by formula I (R 1 and R 2 are 1-2C fluorine-substituted alkyl, 1-10C alkyl, 7-10C aralkyl or 6-10C aryl, provided that at least either of R 1 and R 2 is 1-2C fluorine-substituted alkyl). n EXAMPLE: (1R)-(+)-1-(trans-2-Phenylcyclopropyl)-2,2,2-trifluoroethanol. n USE: A raw material for esters, ethers and carboxylic acids used as an enzymic inhibitor, biologically active substance, anticancer agent and ferroelectric liquid crystal. n PREPARATION: For example, a compound, having triple bond and expressed by formula II is reduced to provide a compound expressed by formula III, which is then acylated to afford a compound expressed by formula IV. The resultant compound expressed by formula IV is further subjected to asymmetric hydrolysis using an enzyme to provide compounds expressed by formulas V and Va. The obtained compound expressed by formula V is then converted into cyclopropane to afford the compound expressed by formula I. n COPYRIGHT: (C)1990,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6096908-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100335134-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102017213259-A1 |
| priorityDate | 1988-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.