| abstract |
PURPOSE: To obtain the subject compound useful for intermediate of physic and agricultural drug with two processes in industrially low cost and high yield by transforming acetophenone compound to haloacetophenone compound and reacting with fluorinating agent. n CONSTITUTION: A compound expressed by formula I (R 1 , R 3 or R 5 is H, F, alkyl, cycloalkyl, alkoxy, alkoxyalkyl, alkylthio, dialkylamino or polyfluoroalkyl; R 2 or R 4 is same as each group in R 1 , R 3 or R 5 except of F, or halogen) is transformed to a compound expressed by formula II (X and Y are halogen; lis 0 or 1; m and n are respectively 0, 1 or 2; l+m+n=3) using halogenating agent, preferably chlorinating agent or brominating agent and reacted with fluorinating agent, preferably fluoride of alkali metal to reasonably obtain the aimed compound expressed by formula III useful as raw material of surfactant or crosslinking agent without need of isolating nor purifying the intermediate. n COPYRIGHT: (C)1990,JPO&Japio |