http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0236186-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46e48a70f5682ddc8379f7145b9693a9 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-21 |
| filingDate | 1988-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67163883a81515835277a29eeabcedd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7f58f731f7c1d3a76740e34d677417e |
| publicationDate | 1990-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0236186-A |
| titleOfInvention | Production of pivmecillinam |
| abstract | PURPOSE: To industrially and advantageously obtain the subject compound by reacting an aminopenicillanic acid with an hexamethylleniminecarboxaldhydedimethylacetal in a solvent, followed by reaction with a halomethyl pivalate in the presence of potassium carbonate. n CONSTITUTION: A 6-aminopenicillanic acid is dispersed in an alcohol solvent such as methanol and a compound expressed by formula I is dropped thereinto under cooling (preferably at 0-5°C) and reacted for 3-5hr to afford to afford a mecillinam expressed by formula II. Then the mecillinam is dissolved in an aprotic polar solvent such as N,N-dimethylformamide, and potassium carbonate and a halomethyl pivalate are dropped thereinto and reacted at 0-25°C for 10-20hr to afford the objective compound expressed by formula III. n COPYRIGHT: (C)1990,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007109483-A |
| priorityDate | 1988-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.