http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0232054-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2de3beee83d9c19278da409b72c777a8 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 |
filingDate | 1988-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34c24145f39c5045b490d87fea9a0255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34628049256aaab225a219993e040d6d |
publicationDate | 1990-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H0232054-A |
titleOfInvention | 5,5-difluoro-6-oxo-pge derivative |
abstract | NEW MATERIAL:The compound of formula I (R 1 is H or 1-8C alkyl; R 2 is single bond or 1-4C alkylene; R 3 is 1-8C alkyl, 4-7C cycloalkyl, phenyl or phenoxy; B is ethylene, trans-vinylene, etc.), its cyclodextrin-clathrate compound or, when R 1 is H, its salt. n EXAMPLE: (11α)-(15S)-(13E)-15-[(1S,3S)-3-butylcyclopentyl)-5,5-difluoro-11,15- dihydroxy-6,9-dioxo-16,17,18,19,20-pentanorprost-13-enoic acid methyl ester]. n USE: An antiulcer agent having exclusively and selectively strong antiulcer activity. n PREPARATION: The compound of formula I can be produced by hydrolyzing a compound of formula II (R 4 is tetrahydropyran-2-yl, tetrahydrofuran-2-yl, etc.) with an acid (e.g., acetic acid) in a solvent (e.g., THF) at 0-90°C. n COPYRIGHT: (C)1990,JPO&Japio |
priorityDate | 1988-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.