http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0232046-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_129e393582e6bdf4029baf2206522f45 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-00 |
| filingDate | 1988-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b5b653876c7137c4e36188184726e81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69a29b6dfb1d388d7a7d783e287a80e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63cc4a72be00890268dd5dd2dbf5f5b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d58d0b448f00eb33e7b7b300c45839a |
| publicationDate | 1990-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0232046-A |
| titleOfInvention | Production of optically active 1-methyl-3-phenyl-propylamine |
| abstract | PURPOSE: To easily perform the optical resolution of (RS)-1-methyl-3- phenylpropylamine via a diastereomer salt in high optical purity and yield by using an optically active cis-2-benzamide cyclohexanecarboxylic acid as a resolution agent. n CONSTITUTION: An optically active 1-methyl-3-phenylpropylamine useful as an intermediate for a drug such as β-blocker can be easily produced in high yield and optical purity by using an optically active cis-2-benzamide cyclohexanecarboxylic acid as a resolution agent, forming two kinds of diastereomer salts of said resolution agent and (RS)-1-methyl-3-phenylpropylamine and carrying out the optical resolution of the (RS)-1-methyl-3-phenylpropylamine taking advantage of the solubility difference between said two kinds of diastereomer salts. The resolution agent can be easily recovered and reused by treating the diastereomer salt with an acid or alkali. n COPYRIGHT: (C)1990,JPO&Japio |
| priorityDate | 1988-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.