http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02306944-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_129e393582e6bdf4029baf2206522f45 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29 |
| filingDate | 1989-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d58d0b448f00eb33e7b7b300c45839a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63cc4a72be00890268dd5dd2dbf5f5b2 |
| publicationDate | 1990-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H02306944-A |
| titleOfInvention | Production of optically active 1-(p-bromophenyl) ethylamine |
| abstract | PURPOSE: To easily obtain the subject compound having high optical purity and useful as an optical resolution agent for racemic acids, in high yield, by using an optically active N-acetyl-2-(p-methylphenyl)alanine as an optical resolution agent. n CONSTITUTION: 1Mol of (RS)-1-(p-bromophenyl)ethylamine is brought into contact with 0.1-2.0mol of optically active (D)- or (L)-N-acetyl-2-(p-methylphenyl)alanine as an optical resolution agent in a solvent (e.g. water or lower alcohol) at 0-80°C to effect the optical resolution of the compound. The obtained solution is cooled and/or concentrated to crystallize scarcely soluble diastereomer salt and the crystal is easily separated by a solid-liquid separation process such as filtration to obtain the objective compound. The above resolution agent can be easily recovered by the treatment with an acid and alkali and the recovered optically active N-acetyl-2-(p-methylphenyl)alanine can be reused. n COPYRIGHT: (C)1990,JPO&Japio |
| priorityDate | 1989-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.