http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02300140-A

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filingDate 1989-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b76bec5c6f6350304c5e407404a95b56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dea777a2d029f4775e7ac18210213ca7
publicationDate 1990-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H02300140-A
titleOfInvention Cyclodextrin clathrate body of drug and production thereof
abstract PURPOSE: To obtain the title clathrate body capable of utilizing an insoluble drug as a rapidly soluble drug and being simple in production process by subjecting drug powder selected from a group of reserpine, nalidixic acid and medazepam to roll blending with cyclodextrins powder under anhydrous conditions and including the drug powder into cyclodextrin powder. n CONSTITUTION: One or two or more kind of powder of drugs selected from a group consisting of reserpine, nalidixic acid, medazepam, phenytoin, triamterene, nifedipine, dichlomalol, griseofulvin and sulfurmethizole is subjected to roll blending with powder of cyclodextrins under anhydrous conditions to include the drugs into cyclodextrin. The cyclodextrins includes especially preferably β-cyclodextrin. The roll blending under anhydrous conditions is carried out by forcibly kneading the abovementioned drug with cyclodextrins in the absence of water or water-containing aqueous medium using a roll blender. The blend ratio of cyclodextrins is 1-3mol based on 1mol drug. n COPYRIGHT: (C)1990,JPO&Japio
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priorityDate 1989-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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