http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02295946-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C63-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C63-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C63-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C63-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-24 |
| filingDate | 1990-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5da1519786d9135bde2c3c157f23f82d |
| publicationDate | 1990-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H02295946-A |
| titleOfInvention | Substituted biphenylcarboxylic acid and its preparation |
| abstract | NEW MATERIAL: A biphenylcarboxylic acid represented by formula I (wherein R 1 is H or OCH 3 ). n EXAMPLE: 4,4'-Difluorobiphenyl-2-carboxylic acid. n USE: A medicine. A material for the synthesis of 2,7-difluoro-9-fluorenone of formula II useful as a medicine used in the treatment of sequelae following diabetes. n PREPARATION: A 2-methoxybenzoic acid of formula III is reacted with an ethanolamine of formula IV (wherein R 1 and R 3 are each H or a 1-3C alkyl, provided that R 2 ≠R 3 = alkyl) to form an amide of formula V. This is then cyclized to form a novel compound of formula VI. This is reacted with an organometallic reagent of formula VII [wherein M is Li, Zn-Hal (wherein Hal is Cl, Br or I) or the like] to form a novel biphenyl derivative of formula VIII, this is optionally converted into a novel alkyl compound of formula IX (wherein R 4 is a 1-3C alkyl; and X - is a chloride ion, a methyl sulfite ion or the like), and the product is hydrolyzed to obtain a compound of formula I. n COPYRIGHT: (C)1990,JPO |
| priorityDate | 1989-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.