http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02292244-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dfd617dc43a4c986d2dd81e4cb39d9dd |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-85 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-00 |
filingDate | 1989-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07bebafc9f24687ff62686ce6b6dcab6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bb500a5a507eda60ed0cbf1d9d34289 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8510f090372b57664e1bf3a4c090a88e |
publicationDate | 1990-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H02292244-A |
titleOfInvention | Production of phenylpropionic acid derivative |
abstract | PURPOSE: To obtain a free acid by treating methyl 3-[p-(trans-4- aminomethylcyclohexylcarbonyl)phenyl]propionate hydrochloride, etc., in the presence of a fungus, etc., belonging to the genus Aspergillus or Mucor. n CONSTITUTION: A compound expressed by the formula (R is benzyl, phenyl, lower alkyl, etc.) or salt thereof is treated in the presence of microbial cells of a microorganism selected from fungi belonging to the genus Aspergillus or Mucor, yeasts belonging to the genus Candida, etc., bacteria belonging to the genus Pseudomonas, etc., and actinomyces, and obtained culture or extract thereof to afford a free acid of the compound expressed by the formula and salt thereof. The abovementioned reaction is carried out in water or a suitable buffer solution at 25 to 35°C for 10 to 15hr while being kept at pH4 to 7. The resultant compound is produced in high purity and yield under mild conditions according to the aforementioned reaction without causing side reaction. The abovementioned method is excellent in safety and simple post-treatment. n COPYRIGHT: (C)1990,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114522115-A |
priorityDate | 1989-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.