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filingDate 1989-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a36545f08fe1643e7309ae051156892b
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publicationDate 1990-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H0228115-A
titleOfInvention Physiologically active substance and pharmaceutical composition containing the same substance
abstract NEW MATERIAL:A physiologically active substance obtained by adding an extracting solvent to poxed tissues, grinding the tissues, removing tissual pieces, deproteinizing the ground tissues, adsorbing the resultant substance on an adsorbent, eluting the adsorbed ingredients, adding an aqueous solution of the eluted ingredients to ethanol, separating and collecting deposited precipitates and fractionating the precipitates with molecular weight. n USE: An analgesic, sedative and anti-inflammatory agents, capable of exhibiting excellent treating effects on various painful diseases, such as pains in neuralgia, osteoarthritis of the knee, other lumbago or rheumarithritis, and having excellent remedial effects by oral administration with low toxicity without any side effects. n PREPARATION: An extracting solvent is added to poxed tissues (e.g., animal tissues poxed by inoculating vaccinia viruses, etc.), which are then ground to remove tissual pieces. The resultant substance is deproteinized and then adsorbed on an adsorbent, such as active carbon or cations, to elute adsorbed ingredients. An aqueous solution (preferably basic solution) of the eluted ingredients is then added to ethanol to separate and collect deposited precipitates, which are then fractionated with molecular weight to afford the objective physiologically active substance. n COPYRIGHT: (C)1990,JPO&Japio
priorityDate 1988-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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