http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02255618-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-472
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47
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filingDate 1989-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc5832d8c5e2c4577a1639053ad7091c
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publicationDate 1990-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H02255618-A
titleOfInvention Remedy for glaucoma
abstract PURPOSE: To obtain the subject agent effective in remarkably lowering the intraocular tension and useful as a remedy for glaucoma by using an isoquinolinone derivative and its acid addition salt as active component. n CONSTITUTION: The objective agent contains an isoquinolinone derivative of formula (R 1 is H or lower alkyl; R 2 is lower alkyl) and its acid addition salt as active component. The acid of the acid addition salt is e.g. HCl, H 2 SO 4 , nitric acid or hydrobromic acid. An example of the compound of formula is 4-(3-t-butylamino-2-hydroxypropoxy)-1-isoquinolinone. The active component of the remedy is administered at a rate of 0.005-2.5mg, preferably 0.025-1.0mg per day for adult in 1 to several divided doses. n COPYRIGHT: (C)1990,JPO&Japio
priorityDate 1989-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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