http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02238896-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_630b360599ea5cf4b5bcbc0c6c0a3e2d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1989-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cb34be44e2c1cd4a11eb348cc0b1e6a |
| publicationDate | 1990-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H02238896-A |
| titleOfInvention | Production of optically active alpha-trifluoromethylcarboxylic acid |
| abstract | PURPOSE: To obtain the title compound useful as an intermediate for drugs, agricultural chemicals, etc., in high optical purity by asymmetrically hydrolyzing an α-trifluoromethylcarboxylic acid ester derivative with a hydrolase. n CONSTITUTION: An α-trifluoromethylcarboxylic acid ester derivative shown by formula I (R 1 is 1-15C alkyl; R 2 is 1-10C alkyl or benzyl) is asymmetrically hydrolyzed with a hydrolase (usually lipase) to give the aimed compound shown by formula II (* is asymmetric carbon atom). The reaction is carried out preferably at 20-45°C generally for 1-300 hours. Hydrolysis ratio is preferably 10-30% in order to raise optical purity of the aimed compound. n COPYRIGHT: (C)1990,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6096908-A |
| priorityDate | 1989-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.