Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7c7159366be37ecf8a4c595cfa235a8 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-08 |
filingDate |
1989-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_843b53d0550468296fd74d6c8721f56c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9238a2393bff83f98a3ed7cc5dca2ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_204dd279acfff1c71649b0ac454f3226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52947bc13b063fd33d61f979a5eb2b18 |
publicationDate |
1990-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H02231096-A |
titleOfInvention |
Human monoclonal antibody |
abstract |
PURPOSE: To provide a human-mouse heterohybridoma NM-3D7 capable of forming a human monoclonal antibody having high antibody titer against intracellular toxin and excellent neutralizing capability. n CONSTITUTION: The objective hybridoma NM-3D7 (FERM P-10517) is prepared e.g. by the preparation of human lymphocyte B cell sensitized with antigen and the establishment of a monoclonal specific antigen-producing cell strain by the impartment of indefinite proliferation capability. The objective human monoclonal antibody can recognize the lipid A site in a ribopolysaccharide molecule of Gram-negative bacteria, bond with lipid X and monophospholipid A and neutralize the activation of a lipopolysaccharide-sensitive protease in the blood coagulation system of Tachypleus tridentatus. n COPYRIGHT: (C)1990,JPO&Japio |
priorityDate |
1989-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |