| abstract |
NEW MATERIAL:Amauroascus sp No.6237 (ATCC No.20595) expressed by formula and its mutant. It has following physical and chemical properties. Elemental analysis (%), C 74.00, H 7.18, N 10.64; molecular weight, 508.2825 (by high- resolution mass spectrometry); molecular formula. C32H36N4O2: melting point, 156-158 deg.C; specific rotation. [alpha] =-583 deg. (c=1, in chloroform); crystal form and color, colorless columnar crystal; etc. USE:A hypotensor, a prophylactic and a gastric juice secretion suppressing agent. PREPARATION:An FR-900220-producing strain belonging to genus Amauroascus is cultured at about 30 deg.C for 50-100hr preferably by submerged culture method using a liquid medium. |