| abstract |
PURPOSE: To obtain a liquid for external use having increased solubility and stability, containing indomethacin and a dissolution auxiliary as essential components. n CONSTITUTION: 0.1-5wt.% indomethacin and 0.3-10wt.% dissolution auxiliary are dissolved in a solvent such as an alcohol, an alcohol-water mixed base or a glycol to give a liquid for external use. One or more are selected from limonene, pinene, camphene, cymene, citronellol, geraniol, nerol, linalool, terpineol, rhodinol, borneol, isoborneol, menthone, camphor, thymol, safrole, isosafrole, eugenol and isoeugenol as the dissolution auxiliary. Indomethacin is an excellent non-steroid-based analgesic antiinflammatory drug. n COPYRIGHT: (C)1990,JPO&Japio |