| abstract |
PURPOSE: To obtain a medicine for preventing, alleviating and treating damage of tissue, comprising inositol triphosphate. n CONSTITUTION: This medicine is obtained by including at least one kind of isomer of inositol triphosphate (IP 3 ), mixing the isomer with a pharmaceutically active compound such as steroids, a gold compound, a penicillamine, an antimalarial agent or an immunosuppressive agent and preparing the mixture. The medicine can be prepared in the form of tablets, granules or solution and contains 0.01-1.5g IP 3 per unit dose. The medicine is useful for tissue damage concerning formation of edema and leakage of blood vessel and also useful for tissue damage concerning burn, rhinitis, asthma, etc. Preferred IP 3 includes D-myoinositol-1,2,6-triphosphate. n COPYRIGHT: (C)1990,JPO |