http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02190195-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d75d1a4caed60a9316608ed9c231546c |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-66 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1989-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0bf117f0e47c2972c284a0ec472ab40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e0f5646a6d972b9989130173e8b7e2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c6703e61472a04c0a6062bdb8f4f57e |
| publicationDate | 1990-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H02190195-A |
| titleOfInvention | Production of optically active propionic acid ester compound |
| abstract | PURPOSE: To easily perform optical resolution by reacting a specific compound with a biocatalyst having asymmetric hydrolysis activity, thereby hydrolyzing one of the optically active isomers. n CONSTITUTION: A biocatalyst such as lipase or immobilized lipase is produced by treating cells of a microbial strain belonging to genus Aspergillus. etc., by extraction, etc. The obtained biocatalyst is added to a water-saturated organic solvent (e.g. benzene) containing 0.5-10wt.% of a racemic propionic acid ester compound of formula [R 1 is acyl (e.g. lower alkanoyl such as acetyl or mono- or di-halogeno-lower alkanoyl such as chloroacetyl); R 2 is ester residue (e.g. lower alkyl such as methyl or ethyl)] and the compound is hydrolyzed at 20-50°C to obtain a reaction liquid. The reaction liquid is treated e.g. by silica gel column chromatography to separate an antipode and obtain an optically active propionic acid ester compound [e.g. optically active threo-3-(4- methoxyphonyl)-3-(2-nitrophenyl-thio)-2-acyloxyproplonic acid ester]. n COPYRIGHT: (C)1990,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5514589-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9825902-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6541242-B1 |
| priorityDate | 1989-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.