http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02188574-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b193a5d74aaedc7cccb46b9840ed86e6 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate | 1989-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69079e5897312a7a426c7dd29705873e |
| publicationDate | 1990-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H02188574-A |
| titleOfInvention | 1,5-benzothiazepine ester derivative |
| abstract | NEW MATERIAL:A compound shown by formula I (R 1 is lower alkyl or lower alkoxy; R 2 is H or halogen; R 3 and R 4 are lower alkyl; n is 2 or 3; R 5 is acyl derived from thioctic acid, linoleic acid, α-linolenic acid, 5,8,11,14,17- eicosapentaenoic acid, 4,7,10,13,16,19-docosahexaenoic acid, 6,9,12,16- octadecatetraenoic acid, 10-undecylenic acid or palmitoleic acid) or an acid addition salt thereof. n EXAMPLE: (+)-cis-2-(4-Methoxyphenyl)-3-linoleyloxy-5-[2-(dimethylamino)ethyl]-2,3- dihydro-1,5-benzothiazepin-4-(5H)-one. n USE: A drug. A remedy and preventive treating agent for circulatory diseases. n PREPARATION: A compound shown by formula II is reacted with a carboxylic acid shown by the formula R 5 -OH in an inert solvent in the presence of a deoxidizer or a condensation agent to give a compound shown by formula I. n COPYRIGHT: (C)1990,JPO&Japio |
| priorityDate | 1989-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.