http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02188526-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a9e9ce63eb0bbf3658453fb50a6d9b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
filingDate | 1989-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_337ee2ec74213046973303132151171d |
publicationDate | 1990-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H02188526-A |
titleOfInvention | Pharmaceutical composition for treating tumor |
abstract | PURPOSE: To prepare a pharmaceutical composition for treating tumor, comprising a tumor necrosis factor(TNF) and dipyridamole or its salt and having enhanced antitumor actions of the TNF. CONSTITUTION: This pharmaceutical composition comprises a TNF composed of TNF-α, TNF-β or a combination thereof and dipyridamole: 2,6-bis(diethanolamino)-4,8-piperidino-pyrimido[5,4-d]pyrimidine or its salt. The ingredients are substantially administered together to a patient suffering from tumor. The preferred amounts thereof in blood plasma for treating the tumor are within the following ranges: 1-5,000U/mL TNF and 0.1-200μM dipyridamole. The TNF is administered as an intamuscular or a subcutaneous injection in preferably about 5×10<6> to 5×10<8> U, more preferably 7×10<6> to 3.5×10<7> U daily dose once and dipyridamole is orally and daily administered in 25-125mg, preferably 30-60mg dose twice. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007508391-A |
priorityDate | 1988-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.