http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02178-A

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filingDate 1989-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3ae23d7f0773e83626431fe8195a62b
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publicationDate 1990-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H02178-A
titleOfInvention Novel aminoalkylbenzene derivative
abstract NEW MATERIAL:The compound of formula I [Y is (OH-substituted) 1- pyrrolidinyl, 1-piperidinyl or 1-perhydroazepinyl; R 1 is H or lower alkyl; Z is =N-CN or =CH-NH 2 ; R 2 is lower alkyl; m is 0 or 1; n is integer of 1-4; group of formula II is bonded to meta- or para-site relative to the group of formula III] or its salt. n EXAMPLE: N-cyano-N'-methyl-N'-[4-[3-(1-piperidinylmethyl) phenoxy]-cis-2- butenyl] guanidine. n USE: An antiulcer agent having excellent gastric inhibitory action originated from histamine H 2 receptor antagonistic action. n PREPARATION: A compound of formula I (Z is =N-CN) is produced by reacting a compound of formula IV or its salt with a compound of formula V (R 4 is lower alkyl) and reacting the resultant compound of formula VI or its salt with a compound of formula R 2 -NH 2 . n COPYRIGHT: (C)1990,JPO&Japio
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022034121-A1
priorityDate 1989-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 33.