http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02172947-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9822bceff022feda91b10019125e70f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-29 |
filingDate | 1988-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86515d63568cc02df8c9e19c0bc2133f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6128c3d9bc774f58a055f00cfe5fd6a0 |
publicationDate | 1990-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H02172947-A |
titleOfInvention | Production of 1-acetoxy-3-chloro-2-propanone |
abstract | PURPOSE: To obtain the subject substance in high yield by reacting 1-acetoxy-2- propyne with acetic anhydride in the presence of a mercury(II) salt catalyst and then reacting the resultant 1,2-diacetoxy-2-propene with hypochlorous acid. n CONSTITUTION: A compound expressed by formula I is reacted with acetic anhydride in the presence of a mercury(II) salt [e.g. mercury(II) acetate] as a catalyst to provide a compound expressed by formula II, which is then reacted with hypochlorous acid under acidic conditions to afford a compound expressed by formula III. The step in the former stage is preferably carried out at ambient temperature using the acetic anhydride as a solvent and a Lewis acid, such as BF 3 -ether complex, in an amount of 1.0-2.0 equiv. based on the mercury(II) salt preferably coexists in order to further improve the yield. The hypochlorous acid is generated from H 2 N-CONHCl-acetic acid, etc., or from sodium hypochlorite, etc., and an acid for use. The compound expressed by formula III is used as an antitumor agent or for synthesizing the skeleton of cephalosporins, etc. n COPYRIGHT: (C)1990,JPO&Japio |
priorityDate | 1988-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID227325121 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID12688263 |
Total number of triples: 18.