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filingDate 1989-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9444e2e0132f1ba352e225bb3080338
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publicationDate 1990-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H02164885-A
titleOfInvention Cis-platinum complex containing 1,3-diaminopropane derivative as ligand
abstract NEW MATERIAL: A compd. represented by formula I [wherein R 1 is 1-6C alkyl or 1-4C alkyloxymethyl; R 2 is 1-4C alkyl or 1-4C alkyloxyethyl, R 1 and R 2 are combined to form a ketal forming group of -CH-O-CR 4 (R 5 )- (R 4 is H or CH 3 ; and R 5 is CH 3 or phenyl), R 3 is an anion of cyclopopane-1,1-dicarboxylic acid, glycolic acid, α-1-4C alkylglycolic acid, 1-4C alkyloxymalonic acid, mesooxalic acid, morpholine-4-ylmalonic acid or d-(1-4C alkyl) aminomalonic acid; and (n) is 0-2]. n EXAMPLE: A platinum complex containing a cyclopropane-1,1-dicarboxylic ligand. n USE: An antitumor agent. n PROCESS: A compd. represented by formula II is reacted with cyclopropane-1,1- dicarboxylic acid in the presence of silver oxide or a silver salt of this acid in water or water to which 10-70% of a water miscible solvent is added at a temp. of 0-60°C under a shading condition. n COPYRIGHT: (C)1990,JPO
priorityDate 1988-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 44.