http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02149546-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-347 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-94 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-347 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-94 |
| filingDate | 1988-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c855e3889018be07ab44ac1d42e3e9de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9441f4eb7ba1f71fca1a5d4d25c9694b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_911183b463278e8b712de7c447c6c48b |
| publicationDate | 1990-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H02149546-A |
| titleOfInvention | Preparation of naphthalene derivative |
| abstract | PURPOSE: To readily, safely and profitably provide the subject compound in reduced operation units in good workability and in a good yield by reacting a dialkoxybenzaldehyde compound with a specific compound and subsequently with an acetylenedicarboxylic acid compound. n CONSTITUTION: A dialkoxybenzaldehyde compound of formula I (R 3 and R 4 are lower alkyl) is addition-reacted with a trialkoxybenzaldehyde compound of formula II (R 5 to R 8 are lower alkyl) and a dialkylacetal in a solvent such as tetrahydrofuran in the presence of an organic lithium compound such as n-butyl lithium. The obtained 2-hydroxybenzylaldehyde.dialkylacetal compound of formula III or a salt thereof is reacted with an acetylenedicarboxylic acid compound of formula IV (R 1 and R 2 are lower alkyl) in the presence of an acid such as p-toluenesulfonic acid in a solvent-free state or in a solvent such as toluene to provide the objective compound of formula V useful as a hyperlipidemia remedy. n COPYRIGHT: (C)1990,JPO&Japio |
| priorityDate | 1988-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.