http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H021474-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb75b0b19820e3833ebdcb31603b242b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 |
| filingDate | 1989-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b0af11fe6f349eb6ebb7d1fdfbb6aa5 |
| publicationDate | 1990-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H021474-A |
| titleOfInvention | Production of synthetic intermediate for 1beta-alkylcarbapenem |
| abstract | NEW MATERIAL:A 4β-(1β-alkyl-2-carboxy-2 propenyl)-2-azetidinone compound expressed by formula II [R 1 is H or (substituted) alkyl; R 2 is (substituted) alkyl; R 3 is H or carboxyl-protecting group]. n USE: A starting raw material for 1β-alkylcarbapenem compounds which are excellent antibiotic substances ad useful as for preventing and treating infectious diseases, etc., in humans and animals. n PREPARATION: A 4-leaving group-substituted-2-azetidinone compound expressed by formula I (R 4 is leaving group) is reacted with a trans-2-leaving group- substituted methyl-3-alkylacrylic acid compound expressed by formula III (R 5 is R 4 ) in a solvent, such as tetrahydrofuran, in the presence of zinc dust and a reducing metal, such as cupric bromide, to afford the compound expressed by formula II in high yield. n COPYRIGHT: (C)1990,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8141532-B2 |
| priorityDate | 1988-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.