http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02138200-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_98d52a9a4866ed80e4d24a596b6b8e8d |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 |
filingDate | 1988-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa087a32c7cd426ba84697e7f2205be8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f592d64899112b1bb45235414f0f9916 |
publicationDate | 1990-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H02138200-A |
titleOfInvention | Neutrophilic chemotactic factor mdncf-2 produced from macrophage |
abstract | NEW MATERIAL: A neutrophilic chemotactic factor MDNCF-2 which is protein having the following properties. Molecular weight: 15,000-25,000 dalton; isoelectric point: pH 4.8; action: neutrophilic action to induce chemical chemotactic reaction; thermal stability: stable in aqueous solution at 56°C for 30 min; amino acid sequence of N terminal: sequence of the formula. n USE: Being inflammation mediator, inflammation can be controlled using a specific antibody to the substance. Indicating antiulcer action, useful for therapy of cancer. n PROCESS: For example, after fluid paraffin being injected into the abdominal cavity of guinea pig, when macrophage penetrates sufficiently, muramyldipeptide is injected into the abdominal cavity to give stimulation to produce MDNCF-2. Next, the crude MDNCF-2 is preferably subjected to ultrafiltration, an ion exchange column, and a reversed phase chromatography in sequence to be purified. n COPYRIGHT: (C)1990,JPO |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-674148-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5891644-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5877284-A |
priorityDate | 1988-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.