http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02138177-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5ad8562c578b061df7a2c3aee9d0e24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-54 |
| filingDate | 1988-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3c7e5015ea160676e8f9def7bf7b49c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_733ca2d27eeb63b42480c33783efa47b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6adf6bf8801c7a4b5541b3c56f4126f |
| publicationDate | 1990-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H02138177-A |
| titleOfInvention | Preparation of noncyclic pyrimidine nucleotide |
| abstract | PURPOSE: To obtain a substance in a high yield by a method in which a pyrimidine derivative, after being treated occasionally with hexamethyldisilazane, is reacted with 2-acetoxyethyl acetoxymethyl ether, etc., in the presence of CsI and an organic solvent. n CONSTITUTION: A compound of formula I (X is S or O; R 1 -R 3 are each H, CH 3 , F or OH; and R 2 can be NH 2 ), after being treated according to circumstances with hexamethyl silazane, is reacted with 2-acetoxyethyl acetoxymethyl ether or O-chloromethyl-1,3-di-O-benzyl glycerin in the presence of CsI and an organic solvent (example: acetonitrile) to obtain a compound of formula II [Z is 2-acetoxyethoxymethyl or 1,3-bis(benzyloxy)-2- propoxymethyl]. The compound of formula II are important as antiviral agents, anticancer drugs, and antibacterial agents and obtained inexpensively in a short time by the above-described method. n COPYRIGHT: (C)1990,JPO |
| priorityDate | 1988-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.