http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02134321-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1e5656dd7bd5861f43bee5dc59aa584 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-435 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 1989-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_968763e0133d4a50fabcdc1ecf6a145e |
| publicationDate | 1990-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H02134321-A |
| titleOfInvention | 6-halo-4-quinolone compound for producing agent for treating osteoartheritis and application such pharmaceutical composition |
| abstract | PURPOSE: To obtain an agent capable of treating osteoarthritis without causing prominent adverse effect by compounding a 6-halo-4-quinolone compound. n CONSTITUTION: This agent is obtained by compounding a compound of formula I or II (R is ethyl, cyclopropyl, NHCH 3 or a phenyl group substituted with F at para position; R 1 is H or a 1-2C alkyl; R 2 is a halogen; A is CH or N; X is O or S; R 3 is methyl when X is O and H when X is S) or an addition base with a pharmaceutically permissible acid or base, e.g. 1-cyclopropyl-7- piperazinyl-6-fluoro-1,4-dihydro-3-carboxy-4-quinolone. The agent enables the therapy both for a single arthrosis and whole peripheral arthroses of an arthritis patient. The agent is administered once a week by injection, and arthrosis infiltration is carried out in initial five days of the week of the injection. Total dose in a week is in a range of 50-500mg, and the treatment is repeated 7-10 times. n COPYRIGHT: (C)1990,JPO |
| priorityDate | 1988-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.