| abstract |
PURPOSE: To obtain a fibrin derived from a patient in a short time and under an almost aseptic condition by treating plasma with an enzyme having a thrombin action and polymerizing and solidifying fibrinogen in the plasma. n CONSTITUTION: Fibrin is prepd. by treating plasma obtd. by passing a collected blood through a plasma separating membrane and the obtd. plasma with thrombin or an enzyme having a thrombin-like action such as reptilase, thereby polymerizing and solidifying fibrinogen in the plasma. In this process, it is pref. to add a substance which inhibits fibrin degradation such as Ca 2+ , FXIII, aprotinin tranexamate. Polymn. using this enzyme is pref. performed in a buffer soln. close to neutrality. n COPYRIGHT: (C)1990,JPO&Japio |