Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a17209ccc336ebb9b67deef73d6609da |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-24 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B55-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-18 |
filingDate |
1988-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_092341c2c06ac816b1b10fb53aaba122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b7d2d624e86417e3fe24acbe78c6b9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20369ea158f8833ba603d7b3c95bf226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8a29e84216fd9275e883c27c6e1044f |
publicationDate |
1990-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H02124881-A |
titleOfInvention |
Racemization of optically active tetrahydrofuran-2-carboxylic acid |
abstract |
PURPOSE: To perform racemization of an optically active tetrahydrofuran- carboxylic acid using an inexpensive reagent on an industrial scale at a low cost without causing undesirable side reaction such as decomposition by heating the carboxylic acid in the presence of a strong base at a high temperature. n CONSTITUTION: An optically active tetrahydrofuran-2-carboxylic acid of formula (* represents asymmetric carbon atom) can be racemized by treating at ≥100°C (preferably at 140-160°C under pressure using water as a reaction medium) in the presence of a strong base (preferably sodium hydroxide or potassium hydroxide of an amount of 1.5-2.5 equivalent at a concentration of 30-60wt.% in the reaction medium). The heat-treatment may be performed by using an organic solvent (e.g., ethylene glycol) having a boiling point of >100°C as the medium and heating at a temperature below the boiling point of the solvent under normal pressure. n COPYRIGHT: (C)1990,JPO&Japio |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10370387-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017514832-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021100930-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006522014-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11161855-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10450325-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11304949-B2 |
priorityDate |
1988-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |