| abstract |
PURPOSE: To obtain therapeutic medicine for cerebral apoplexy containing a compound that acts as a serotonin agonist and has a specific bond strength in bonding with a 5HT 1 A receptor. n CONSTITUTION: This therapeutic medicine for cerebral apoplexy contains an active compound that acts as a serotonin agonist and has a bond strength of 10000nmol/l or less in bonding with a 5HT 1 A receptor, for example, (het) arylpiperazine, aminotetrahydro-benzindole, indoleamine, aminoalkylbenzodioxane, aminotetraline, aminochroman, aminothiopyran or indolylalkyl-piperazine. Any of these compounds is preferably administered in a quantity of 0.01-0.5mg/kg of body weight in a case of intravenous infection or 0.1-10mg/kg in a oral dose. n COPYRIGHT: (C)1990,JPO |