http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02117625-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2becae6007cc3e5659354fe53b4c560c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B43-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-22 |
| filingDate | 1988-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a118c3e2252be737001848efdcc027c |
| publicationDate | 1990-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H02117625-A |
| titleOfInvention | Production of peptide or acid amide compound |
| abstract | PURPOSE: To obtain a peptide or acid amide compound in good yield by reacting an active ester of a protected amino acid or peptide with an amine or imine using a mixed system of water and an organic solvent compatible therewith as a solvent. n CONSTITUTION: An active ester expressed by formula I (A is residue of amino acid or peptide; R is protecting group at the N-terminal of amino acid or peptide) is reacted with an amine or imine expressed by formula II (B and D are H or organic group or both, together with the adjacent N, may form heterocyclic ring) using a mixed system of water and an organic solvent (e.g., dimethylformamide, chloroform, dioxane or tetrahydrofuran) compatible therewith as a solvent to afford a peptidic compound or acid amides expressed by formula III (e.g., benzloxycarbonylalanylamide). Protection of the C-terminal can be omitted and the process is simplified to improve yield. Thereby, the above-mentioned method is industrially advantageous. n COPYRIGHT: (C)1990,JPO&Japio |
| priorityDate | 1988-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.