http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0211568-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97ddd4d1d0ebc8a7d2c8e7d214d08cf3 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 |
| filingDate | 1988-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9e626262e0195bc3cf3584e67e456cf |
| publicationDate | 1990-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0211568-A |
| titleOfInvention | 2-pyridylacetic acid derivative |
| abstract | NEW MATERIAL:A 2-pyridylacetic acid derivative shown by formula I [R 1 is 8-15C aralkyl or -(CH 2 ) n -A (n is 0-3; A is benzocyclobutyl, indanyl or tetrahydronaphthyl); R 2 is H or 1-5C alkyl] and an acid addition salt thereof. n EXAMPLE: Phenethyl 2-methylthiocarbamoyl-2-(2-pyridyl)acetate. n USE: Useful as a remedy for peptic ulcer having inhibitory action on secretion of acid in the stomach and protecting action on gastric mucosa and low toxicity free from side effects. n PREPARATION: A 2-pyridylacetic ester shown by formula II is treated with carbon dioxide in an organic solvent in the presence of a base at -78°C-0°C. Then the resultant compound is reacted with methyl iodide to give a compound shown by formula III. Successively the compound shown by formula III is reacted with a compound shown by formula IV in water or organic solvent or a mixture thereof to give a compound shown by formula I. n COPYRIGHT: (C)1990,JPO&Japio |
| priorityDate | 1988-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.