http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02111741-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9822bceff022feda91b10019125e70f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_065fe7c4146d471ac47823ff7c1d911f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B55-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-353 |
| filingDate | 1988-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d9738a9f17fd663da29c821af352dc8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0bec6dc7e7ed6bd19e87ba60f7f4fc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e82a465094da06726accec6328282fee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbc6aa64d743a8a094e749aa06a1e2f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e30e3b3b76f0d6b12a7e8378a0da26a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8545da6aaa25d2c4f09c10df3b1f791e |
| publicationDate | 1990-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H02111741-A |
| titleOfInvention | Racemization of optically active 2-(1-naphthylmethyl) succinic acid |
| abstract | PURPOSE: To readily provide (RS)-2-(1-naphthylmethyl)succinic acid useful as an raw material for medicines by subjecting (S)-2-(1-naphthylmethyl)succinic acid to a conversion reaction into an ester, to a treatment with a base to racemize the prepared ester and further to a hydrolysis reaction. n CONSTITUTION: An optically active compound of formula I [the C atom having a subscript of (S) has a (S)-arrangement] is treated with an alcohol, preferably methanol, under an acidic condition to convert into an ester of formula IX (R 4 is alcohol residue), which is treated with a base such as an alkali alcoholate or an alkaline earth metal alcoholate to give a racemic compound of formula X [(RS) exhibits to be a racemic compound]. The compound of formula X is hydrolyzed and subsequently optically resolved to readily provide a racemic compound of formula II which can be derived into an optically active compound of formula III [the C atom having a subscript of (R) has a (R) arrangement] useful as a raw material for a hypertension remedy. n COPYRIGHT: (C)1990,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5278334-A |
| priorityDate | 1988-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.