| abstract |
NEW MATERIAL: A compound of formula I (R<1> is H, hydroxy, a 1-6C alkoxy, etc.; R<2> is H, a halogen, cyano, an azide, etc.; R<3> is H, a 1-6C alkyl, a 1-6C alkenyl, etc.; A is formula II, a 6-17C alkylene, etc.) and its salt. EXAMPLE: 11-(3-Methyl-4-oxo2-oxetano)3,5,7-trimethyl-2,4undecadienoic acid. USE: Useful for the treatment of the state of diabetic ketoacidosis. PREPARATION: A compound of formula I and its salt (e.g. a salt formed from a cation such as sodium, potassium or aluminum or a base such as hydroxy tetramethylammonium) is obtained by fermentation with the fungi ATCC 1233 and a standard chemical conversion. |