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publicationDate 1990-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H02101081-A
titleOfInvention Crystalline dihydrochloride of cephalosporin derivative and production thereof
abstract NEW MATERIAL:Crystalline dihydrochloride of (6R,7R)-7-[(Z)-2-(2-aminothiazol-4- yl)-2-((1S)-1-carboxyethyoxyimino)acetamido]-3-[(1-ethylpyridinium-4-yl) thiomethyl]ceph-3-em-4-carboxylate. n USE: An antibacterial agent against Gram-positive and Gram-negative bacteria. n PREPARATION: (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-((1S)-1-carboxyethoxyimino) acetamido]-3-[(1-ethylpyridinium-4-yl)thiomethyl]ceph-3-em-4-carboxylic acid having protected amino and carboxyl groups is deprotected and then crystallized from an aqueous solution of hydrochloric acid. n COPYRIGHT: (C)1990,JPO&Japio
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