http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0196176-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dae64c775f32c43199adbb4389c2c9b3 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D301-02 |
| filingDate | 1987-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55d90ee2ea31c5e53f22f61211a9f321 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7c28d28738a15b837618239da095e33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a42cf1c0aa0b43b996acf06cc68fdf0f |
| publicationDate | 1989-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0196176-A |
| titleOfInvention | Production of optically active epihalohydrin |
| abstract | PURPOSE: To obtain the titled compound by a simple operation in easy recovery and reuse of oxygen, by using an organic solvent suspending an enzyme and carrying out three processes from a racemic modification of a 3-halo-2-acyloxy-1- alkyl (or aryl)sulfonyloxypropane. n CONSTITUTION: A compound shown by formula I (X is halogen; R is aliphatic hydrocarbon; Y is aromatic hydrocarbon or aliphatic hydrocarbon) is subjected to enzymatic alcoholysis in an organic solvent suspending an enzyme such as lipase to give a mixture of an (S)-alcohol shown by formula II and an (R)- ester shown by formula III, then the enzyme is filtered off from the mixture, which is treated with an organic solvent-alkali aqueous solution two layer system to give an (S)-epihalohydrin shown by formula IV, further the compound shown by formula IV is distilled away from the organic layer and a compound shown by formula III contained in the residue is treated with an alkali to give an (R)-epihalohydrin shown by formula V. This compound is useful as a synthetic intermediate for optically active substances having physiological activity. n COPYRIGHT: (C)1989,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5629423-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6057476-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9812171-A1 |
| priorityDate | 1987-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.