Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8a8f16522cbf08213cf1ab3ff3dd6d8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 |
filingDate |
1987-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_904925c02627a1ebef4cb5b0dd9e1f29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9dcff6403f2dfd49d75d12f16a7f76d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54d589dc144136d04c764a18015e0c41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_941bca9c55be395e16ccadd8af420c93 |
publicationDate |
1989-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H0193525-A |
titleOfInvention |
Antifungal agent composition |
abstract |
PURPOSE: To obtain an antifungal agent composition containing an azole-based antifungal agent and an arylmethylamine-based antifungal agent, showing excellently synergistic effects by using both the antifungal agents and having fungistatic action and fungicidal action with a small drug amount. n CONSTITUTION: An azole-based antifungal agent is blended with an arylmethylamine-based antifungal agent in the weight ratio of 100/1W1/500, preferably 25/1W1/25. Increase in the ratio of the arylmethylamine-based antifungal agent having low toxicity provides synergistic effects and can especially preferably reduce toxicity of drug. The aimed substance can be pharmaceutically manufactured by adding 0.1W10.0wt.% of the aimed substance to an ordinary pharmaceutical carrier. N-4-tert-Butylbenzyl-N-methyl-1- naphthalenemethylamine may be cited as the arylmethylamine-based antifungal and miconazol as the imidazole-based antifungal agent. The antifungal agent composition is useful for treating mycosis caused by a fungus belonging to the genus Candida, Aspergillus or skin mold. n COPYRIGHT: (C)1989,JPO&Japio |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002114680-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6087390-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005032530-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9852957-A1 |
priorityDate |
1987-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |