http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01311087-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27176f5bbbfd702de498d84df8ff3ae5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-10 |
| filingDate | 1988-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9760307052477bb75e583e75204197e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b4badd99f78ecaa3cecb969d3f0207c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b036c2d5e4d7735d248501ba3bef2b0 |
| publicationDate | 1989-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H01311087-A |
| titleOfInvention | Production of phosphatidylcholine |
| abstract | PURPOSE: To contrive simplification and high yield in a reaction process of the subject compound useful as cosmetics and medicines by reacting glycerophosphocholine with an acyl chloride in the presence of hexamethylphosphoric triamide. n CONSTITUTION: For example, in the presence of 10-40mol equivalents hexamethylphosphoric triamide (preferably dehydrated by an addition of molecular sieves in use) as a reaction solvent as well as a proton acceptor, 1mol equivalent dry glycerophosphocholine (obtained from a native phosphatidylcholine by deacylation) is dispersed and 1.6-6mol equivalents acylchloride (one without causing isomerization at an aliphatic or aromatic site) are added thereto and the reaction is carried out preferably at 40-60°C for 1-3hr, followed by purification of the resultant reaction product by silicic acid column chromatography with a gradient chloroform/methanol to afford the aimed compound. n COPYRIGHT: (C)1989,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0609078-A1 |
| priorityDate | 1988-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.