http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01301660-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ae96c0ecc22ff90ff986371a3cea0f |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D521-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
| filingDate | 1988-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf91855aefdc053d39db23e5664f8827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2776c8a03b1912fbd2d01453473b174f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1cfef30f0c36908a956f371a12eb3e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9628fa307f24b2c617b0f8633ccde24d |
| publicationDate | 1989-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H01301660-A |
| titleOfInvention | Selective production of optically active alanine ester derivative |
| abstract | PURPOSE: To obtain the subject compound useful for intermediate of drug in optically high purity and high yield without reagent of high cost, by reacting a mixture of D-modification and L-modification of a monocyclic heterocyclic alanine esters containing 3-nitrogen with an enzyme having esterase activity. n CONSTITUTION: A mixture of D- and L-modifications of monocyclic heterocyclic alanine ester containing 3-nitrogen and salts of said ester (e.g., salt of HCl, H 2 SO 4 , nitric acid or phosphoric acid) is reacted with an enzyme having esterase activity (e.g., α-chymotrypsin, subtilisin) preferably at about neutral and a temperature of near 37°C, in a solvent having no adverse effect to the reaction. By said method, only L-modification of said mixture is selectively deesterified and D-modificationis obtained. n COPYRIGHT: (C)1989,JPO&Japio |
| priorityDate | 1988-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.