| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5ffa3f9d6b87e15e0a1551fb129b531 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-54 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate |
1989-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ed8c05660d5face70e4c0b770226593
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5a141afba4efb7d5c1d417d631f7c6f |
| publicationDate |
1989-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H01299230-A |
| titleOfInvention |
Aqueous solution of pharmaceutical composition of piroxicam and its production |
| abstract |
PURPOSE: To prepare an aqueous solution of pharmaceutical composition, usable for injection or ophthalmic applications and having a high local tolerability by dispersing piroxicam which is a nonsteroidal antiinflammatory agent in water, adding an alkali(ne earth) metallic hydroxide thereto under stirring and completely dissolving the alkali(ne earth) metallic hydroxide therein. n CONSTITUTION: Piroxicam [chemical name: N-(2-pyridyl)-2-methyl-4-hydroxy-2 H-1,2-benzothiazine-3-carboxamide 1,1-dioxide] is dispersed in water at a concentration within the range of 1-4wt./vol.% and an aqueous solution of an alkali(ne earth) metallic hydroxide, preferably a 1N NaOH in a stoichiometric amount is then added thereto under stirring and completely dissolved therein. The aqueous solution is in the form of a directly usable solution or a freeze-dried state for dissolving in distilled water for injection before use and contains 10-30mg active ingredient in a dose at a time or at 0.2-1% concentration of the active ingredient. n COPYRIGHT: (C)1989,JPO |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9943486-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10548901-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003535902-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9801139-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005511720-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9993557-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6235724-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9795568-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10098891-B2 |
| priorityDate |
1988-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |