| abstract |
PURPOSE: To obtain a suppressant of cancerous cell metastatsis, extremely excellently suppressing metastasis of cancerous cell, having extremely low cell disorder, comprising nojirimycin, mojirimycin sulfite adduct, etc., as an active ingredient. n CONSTITUTION: A suppressant of cancerous cell metastatsis containing nojirimycin (5-amino-5-deoxy-D-glucopyranose) shown by the formula (Z is OH, SO 3 H or H; one of R 1 and R 2 is OH and the other is H), nojirimycin sulfide adduct, nojirimycin B (5-amino-5-deoxy-D-mannopyranose), nojirimycin B sulfite adduct of 1-deoxynojirimycin as an active ingredient. The suppressant can extremely raise carcinostatic effects by simultaneous administration with an existing carcinostatic agent and using the suppressant during surgical therapy or radiation therapy and 100gW3,000mg suppressant is administered once or several time daily. n COPYRIGHT: (C)1989,JPO&Japio |