http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01265024-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97ddd4d1d0ebc8a7d2c8e7d214d08cf3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-59 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-55 |
| filingDate | 1989-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9e626262e0195bc3cf3584e67e456cf |
| publicationDate | 1989-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H01265024-A |
| titleOfInvention | 2-pyridylacetic acid derivative and medicine containing same |
| abstract | NEW MATERIAL:The compound of formula I [R 1 is -(CH 2 ) m -cycloalkyl having 5-8C cycloalkyl which may be substituted with 1-6C alkyl (m is 0-4); R 2 is H or 1-10C alkyl] and its acid addition salt. n EXAMPLE: Cyclopentylmethyl 2-pyridylacetate. n USE: A medicine for peptic ulcer. It has gastric inhibitory action and gastric mucosa protecting action and exhibits weak toxicity. Accordingly, it is useful for the remedy of peptic ulcer. n PREPARATION: The objective compound of formula I can be produced by (1) reacting a 2-pyridylacetic acid ester of formula II with carbon disulfide in a solvent (e.g. THF) in the presence of a base (e.g. alkyllithium reagent) at -78-0°C, (2) adding methyl iodide to the reaction mixture and stirring to obtain a compound of formula III and (3) reacting the compound with ammonia or amines of formula R 2 -NH 2 in a solvent (e.g. water or alcoholic solvent) for 1-10hr. n COPYRIGHT: (C)1989,JPO&Japio |
| priorityDate | 1988-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.