http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01261364-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_324beb8b942a3a6ed1f1f576bcd76c45 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-397 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 |
| filingDate | 1988-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_691d17003b2213d06f7bf7a1d19caf4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f97f6e94535872a7684b81811b5e5aee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a04575e5e91bf33d9c70ec79f22ad57e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8a2ec84de2e9d82cd3475dcd3e92e81 |
| publicationDate | 1989-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H01261364-A |
| titleOfInvention | Novel azetidinone derivative and muscle relaxant containing said derivative |
| abstract | NEW MATERIAL:An azetidinone derivative expressed by formula I (R 1 is straight or branched chain alkyl or aryl which may have a substituent group; R 2 is aryl which may have a substituent group; R 3 and R 4 are 1W6C alkyl or 4-W8-membered heterocyclic ring as NR 3 R 4 which may contain other hetero- atoms; n is 2, 3 or 4). n EXAMPLE: cis-3-Benzamido-4-phenyl-1-(3-piperidinopropyl)-2-azetidinone. n USE: A muscle relaxant. n PREPARATION: A compound expressed by formula (a) (X is halogen) is reacted with a Schiff base expressed by formula (b) (Y is halogen or NR 3 R 4 ) in the presence of a base, such as triethylamim, in a solvent without participating in the reaction to afford a compound expressed by formula (c). The imide group in the resultant compound is then converted into amino group in an alcohol using hydrazide hydrate to provide a compound expressed by formula (d), which is further acylated and reacted with an amine expressed by the formula NHR 3 R 4 (Y is halogen) to afford the compound expressed by formula I. n COPYRIGHT: (C)1989,JPO&Japio |
| priorityDate | 1988-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.