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filingDate 1988-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3f8f5c945978e146ad3a97276e35db6
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publicationDate 1989-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H01258699-A
titleOfInvention Bradykinin derivative and determination thereof
abstract NEW MATERIAL:A peptide (salt) expressed by the formula [X is H or Lys (Lys is lysin); Arg is arginine; Pro is proline; Hyp is hydroxyproline; Gly is glycine; Phe is phenylalanine; Ser is serine residue]. n USE: A diagnostic agent for disease accompanying inflammation of cancer, etc. and rising vascular permeability. n PREPARATION: Boc-L-amino acid (Boc is tert.-butyloxycarbonyl) is successively coupled with e.g., p-methylbenzhydrylamine resin used as a solid phase carrier according to the amino acid sequence of peptide and then the peptide is eliminated from the carrier to afford the peptide expressed by the formula, which is then used as a binder and bonded to a protein such as bovine serum albumin to provide the peptide-protein bonded product used as a hapten antigen for preparing an antibody. n COPYRIGHT: (C)1989,JPO&Japio
priorityDate 1988-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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