http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01258683-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02f898efce374bc95f1057a3af5d4080 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 1989-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa145e0324c42b5fbaf25c61b32baae3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_695b715d23299ec1bb72936db8523881 |
| publicationDate | 1989-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H01258683-A |
| titleOfInvention | Production of 7-d(-)-alpha-amino-alpha-(p-hydroxypheny) acetamido-3-(1,2,3-triazol-4(5)-thiomethyl-3-cephem-4-carboxylic acid 1,2-propylene glycolate and new intermediate for producing the same |
| abstract | PURPOSE: To easily obtain the subject compd. by a direct synthesizing method by allowing a specified compd. to react with hydroxyphenylglycyl chloride hydrochloride, allowing the produced precipitate to react with a specified compd. in propylene glycol and then adding water thereto. n CONSTITUTION: A 7-amino-3-halomethyl-3-cephem-4-carboxylic acid of formula I (X is Br or I) is allowed to react with D(-)-p-hydroxyphenylglycyl chloride hydrochloride hydrochloride of formula II to obtain 7-D(-)-α-amino-α-(p- hydroxyhenyl) acetamido-3-halomethyl-3-cephem-4-carboxylic acid. At this time, in the case the group X is Cl, it is furthermore treated with an iodine donor compd. The obtd. compd. is allowed to react with 1,2,3-triazole-4(5)-thiol sodium salt of formula IV, water is added to the reaction mixture, and the precipitated products are isolated to obtain cefatrizine propylene glycolate of formula V. n COPYRIGHT: (C)1989,JPO |
| priorityDate | 1988-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.