http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01254625-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435
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filingDate 1988-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1d9f18dc91b06098316347f51a0699c
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publicationDate 1989-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H01254625-A
titleOfInvention Anti-allergic agent
abstract PURPOSE: To obtain an anti-allergic agent effective in remedying allergic diseases such as bronchial asthma or collagen diseases, by using benzoylmesaconine as an active component. n CONSTITUTION: The objective agent contains the compound of formula I (Bz is group of formula II) which is a component of the extract of SHUJIBUSHI (a chinese herb drug). The anti-allergic agent is administered as an oral drug at a rate of 5W500mg of said compound per day in several divided doses or as a parenteral drug at a rage of 0.5W100mg per day by intravenous injection, intravenous drip, subcutaneous injection or intramuscular injection. The compound of formula I can be produced by extracting SHUJIBUSHI with a solvent (e.g., methanol or n-hexane), distilling out the solvent, fractionating the obtained extract with ammonia water and chloroform, extracting the chloroform-soluble fraction with the above solvent, subjecting the solvent-insoluble fraction to chromatography, developing by using methanol, ethyl acetate, benzene, chloroform, etc., as elution solvents, collecting the fraction containing the objective compound and recrystallizing the compound. n COPYRIGHT: (C)1989,JPO&Japio
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