http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01246297-A

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filingDate 1989-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_519906cd4c5eaa08a8dad9a7b7d1960e
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publicationDate 1989-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H01246297-A
titleOfInvention Production of beta-2',2'-difluoronucleosides
abstract PURPOSE: To obtain the β-isomer of the compd. useful as an antiviral agent by treating the racemic mixture of a specific component with an adenosinedeaminase, etc. n CONSTITUTION: The racemic mixture of the compd. expressed by formula I (R is amino, H) is preferably dissolved in a polar solvent, such as alcohols or water. The adenosinedeaminase is added thereto and reaction is effected preferably for 1 to 4 hours at 20 to 50°C and, if desired, the 6-keto group of the product is aminated, thereby the β-isomer of the compd. expressed by formula II is obtd. n COPYRIGHT: (C)1989,JPO
priorityDate 1988-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 26.