| abstract |
PURPOSE: To obtain optically pure racemic alcohols by reacting a specific vinyl ester with racemic alcohols of a prescribed general formula in the presence of a lipase from a microorganism and isolating racemic alcohols. n CONSTITUTION: A vinyl ester of formula I (R 1 is a 1-18C alkyl group, a phenyl group, a 1-3C alkoxy group, etc.; R 2 is methyl, etc.), is reacted with an alcohol of formula II (R 3 is a 1-18C alkyl group, etc.; R 4 is an epoxy group, etc.; R 5 and R 6 are each a 1-4C alkyl group, alkoxy, a phenyl, etc.), in the presence of a lipase such a lipase from a swine liver. A prepared optically active alcohol of formula II is isolated to give the objective racemic alcohol. n COPYRIGHT: (C)1989,JPO |